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KMID : 0604520210470030265
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Journal of the Society of Cosmetic Scientists of Korea
2021 Volume.47 No. 3 p.265 ~ p.271
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Application of Nanoparticles Derived from Artemisia princeps for Cosmetic Products
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Jung So-Young
Kang Hae-Ran
Yoo Han-Jun
Choi Hyeong
Heo Hyo-Jin
Cha Byung-Sun
Brito Sofia
Lee So-Min
Yeo Hye-Lim
Kang Seo-Jeong
Lee Dae-Yeop
Kwak Byeong-Mun
Lee Mi-Gi
Bin Bum-Ho
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Abstract
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Nanoparticles are substances that are smaller in size and smaller than cells that make up the skin. Therefore, they are very suitable as mediators for transmitting drugs or genes across cell membranes, and also deliver specific ingredients into the skin.In this study, nanoparticles were extracted from mugwort and particles of around 100 nm were obtained through dynamic light scattering (DLS), and the results of concentration-dependent enhancement of cell viability in fibroblasts were obtained through MTT assay. In addition, it was confirmed that the COL1A1 mRNA expression level was increased and the IL-6 mRNA expression level was decreased through the quantitative real-time PCR analysis method. Moreover, as these nanoparticles were confirmed to be stable, they can be applied not only to cell experiments but also to cosmetic formulations. While the demand for plant-derived ingredients continues to increase, excluding chemical ingredients from the recent cosmetics industry trend, there is a limitation in that there are few research results suggesting the application field of plant-derived nanoparticles. Therefore, in order to overcome the limitations of the cosmetic industry at the present time, the results obtained in this study present nanoparticles derived from Artemisia princeps (NDAP) as a highly functional cosmetic material.
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KEYWORD
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nanoparticles derived from Artemisia princeps (NDAP), cosmetic material, anti-aging, nanoparticle, natural ingredients
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